Original Title: "Net Red" in Medical Materials Industry — — Titanium Alloy Biomedical materials refer to materials that interact with biological systems to diagnose, treat, repair or replace tissues and organs in the body or to enhance their functions. It can be divided into medical metal materials, medical polymer materials, medical ceramic materials and so on, among which medical metal materials account for a large proportion, especially orthopaedic products and cardiovascular and cerebrovascular products. [1] In particular, titanium alloys with high strength, low density, non-toxic, good biocompatibility and corrosion resistance have been used in the medical field, and become the preferred materials for artificial joints, bone trauma, spinal orthopaedic internal fixation systems, dental implants, artificial heart valves, interventional cardiovascular stents, surgical instruments and other medical products. Advantages of Medical Titanium Alloys [2] ① Biocompatibility: It has the smallest biological reaction with the human body, is non-toxic and non-magnetic,ti6al4v eli, and has no toxic and side effects on the human body as a human implant. ② Mechanical properties: High strength and low elastic modulus, which not only meet the mechanical requirements, but also are similar to the elastic modulus of human natural bone, which can reduce the stress shielding effect and is more conducive to the growth and healing of human bone. ③ Corrosion resistance: The titanium alloy is a biologically inert material, which has good corrosion resistance in the physiological environment of the human body and does not pollute the physiological environment of the human body. ④ Light weight: Generally, the density of titanium alloy is only 57% of that of stainless steel, which greatly reduces the load of human body after implantation. Development History of Biomedical Titanium Alloy Biomedical titanium alloys have been widely used in the medical field because titanium is close to human bone,titanium filler rod, has good biocompatibility to human tissues, has no toxic side effects, and has incomparable advantages over other materials. Metallic materials, as biomedical functional materials, are an important branch of materials science, which have been used in human implants for more than 400 years. Biomedical titanium alloys have gone through three stages: pure titanium and Ti-6Al-4V titanium alloy, modified titanium alloy and low modulus β titanium alloy. 1950-1980: Pure titanium was first used in the biomedical field, demonstrating good biocompatibility. Ti6Al4V is widely used as a surgical repair or replacement material. 1980-1990: It was proved that V and Al were elements with toxic side effects on organisms, and the second generation of improved new medical titanium alloy with Nb and Fe instead of V was developed. 1990-present: In the early 1990s, the first beta titanium alloy Ti13Nb13Zr with better biocompatibility and lower elastic modulus was developed, which initiated the development and use of biomedical beta titanium alloys with excellent properties. [3-4] Medical applications of titanium and its alloys [5-7] In recent years, titanium and its alloys have been developing rapidly in the medical field, especially in orthopedics, ti6al4v ,titanium bar grade 5, dentistry and various medical devices.Journal of Chongqing University of Technology ，2016,30（4）：28-34. [2].C. Rhines ,M. Pitters . Translated by Chen Zhenhua et al . Titanium and titanium alloy [M]. Beijing Chemical Industry Press, 2005. [3]. Public information -Wikipedia, Baidu Encyclopedia. [4]. Zhang Wenyu . Research Progress of Biomedical Titanium Alloy [J]. Chemistry and bonding ,2014,35（5）：369-373. [6] Cao Dao Ying Wu. Titanium metal and its applications [M]. Beijing Metallurgical Industry Press, 1989. [7] Wang Tao, Dai Pinqiang, Xiang Zhongnan, et al. Biomedical Superelasticity of Ti-Nb-Sn alloy. Journal of Materials Science and Engineering ,2008,26(6):940-945. [8]. Li Hongmei Thunder, Fang Shuming, Huang Guangming. Research Progress of Biomedical Titanium Alloy [J]. Metallic functional materials ,Titanium 6Al4V wire,2011,18（2）：70-73. Return to Sohu , see more Responsible Editor:. yunchtitanium.com