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Hydrocodone Acetaminophen 5-325 español is a powerful combination of opioid and non-opioid pain relief medications. It's prescribed to treat moderate to severe pain, like the type caused by injuries or surgery. It medication works by blocking the transmission of pain signals from the brain to other parts of the body, providing relief from discomfort. It also contains acetaminophen, which can help reduce fever and inflammation associated with certain types of pain.